Underlying mechanisms of pituitary–thyroid axis function disruption by chronic iodine excess in rats

J Calil-Silveira, C Serrano-Nascimento, RC Laconca… - Thyroid, 2016 - liebertpub.com
… and activity of different proteins in the thyroid gland. Therefore… T4 deiodination both in the
thyroid and in peripheral tissues. … detrimental to thyroid function in iodine-deficient populations (…

Iodine in Disruption of Thyroid and Thyroid Hormone Receptive Systems

AK Chandra - Proceedings of the Zoological Society, 2021 - Springer
… There are studies to evaluate thyroid functions in iodine deficient … The type 2 iodothyronine
deiodinase is expressed primarily … on thyroid function and oxidative stress in hypothyroid rats. …

Detection of some hormonal and enzymatic disorders associated to experimentally iodine induced hyperthyroidism

DS Foda, NE Ibrahim - Egyptian Journal of Chemistry, 2021 - journals.ekb.eg
… mainly in iodine deficient areas in spite of the thyroid gland … the type III deiodinase (DIO3)
enzyme in heart tissues during … in heart failure in rats resulted in a local hypothyroid case [46]…

Defending effects of iodide transfer in placental barrier against maternal iodine deficiency

Y Sun, Y Han, M Qian, Y Li, Y Ye, L Lin, Y Liu - Thyroid, 2021 - liebertpub.com
… with rat placentas before the onset of fetal thyroid function, the regulatory effects of the fetal
side of an iodine-deficientThyroid hormone transporters and deiodinases of placental …

[HTML][HTML] Iodine excess exposure during pregnancy and lactation impairs maternal thyroid function in rats

C Serrano-Nascimento, RB Salgueiro… - Endocrine …, 2017 - ec.bioscientifica.com
… fetal tissues even before the full development of fetal thyroid … /or deiodinases activity in
these organs cannot be ruled out. … pregnancy/lactation in iodine-deficient areas. In conclusion, …

Iodotyrosines Are Biomarkers for Preclinical Stages of Iodine-Deficient Hypothyroidism in Dehal1-Knockout Mice

C González-Guerrero, M Borsò, P Alikhani, Y Alcaina… - Thyroid, 2023 - liebertpub.com
… deficiency only in the thyroid tissue. Under normal iodine … thyroid, kidney, and liver, sites
of reported IYD activity. At E13.… of hypothyroidism and goiter due to iodotyrosine deiodinase (…

Mechanism of multi-organ compensation under different iodine intake in pregnant rats: results from a repeated-measures study of iodine metabolism

M Fu, H Zhang, Y Gao, R Yang, Q Meng, Q Jin… - European Journal of …, 2024 - Springer
… statuses and the role and regulation of NIS and Pendrin gene expression in related events.
… levels compared within the thyroid tissue [30,31,32]. In iodine-deficient rats, the expression of …

[HTML][HTML] Comparative analysis of thyroid hormone systems in rodents with subterranean lifestyle

P Gerhardt, S Begall, C Frädrich, K Renko… - Scientific Reports, 2023 - nature.com
… hepatic deiodinase expression showed many peculiarities in mole-rats, we analysed the
activity of DIO1 in liver tissue. … Albeit iodine deficient, naked mole-rats showed the lowest Tshb …

Excess iodine intake: sources, assessment, and effects on thyroid function

J Farebrother, MB Zimmermann… - Annals of the New …, 2019 - Wiley Online Library
… autoimmunity in previously iodine-deficient areas may occur … in the peripheral tissues by T4
deiodination.109 Iodine … organification of iodide in the rat thyroid was blocked when plasma …

[HTML][HTML] Selenium, iodine and iron–essential trace elements for thyroid hormone synthesis and metabolism

J Köhrle - International journal of molecular sciences, 2023 - mdpi.com
… and the deiodinase-mediated (in-)activation of thyroid hormones, … functional thyroid tissue
and fibrosis with the consequence of … by experimental studies in rats, which revealed that high …